Aim of this work is to report some interesting reference and document related m RNA vaccine. Every cited reference can act as an instrument to better understand what some independent researcher found: this work is mainly focused on the public debate related presence/absence of graphene derivates in some vaccine vials for covid-19. Relevant classic article or White paper or other kind of document are useful instrument to better clarify Some crucial aspects of this infectious disease, its epidemiology and efficacy of the measure adopted(preventive, therapeutic or vaccine). If the reviewed article show an intrinsic recognized international value other kind of source like White Paper or other document can be of interest to generate hypotesys or to open public discussion on crucial topics. For this reason it is useful to use this method also in the discussion related of impurity profile in new innovative bio-pharmaceuticals like the m RNA vaccine.

M. Luisetto, Dottore in Filosofia, Vicepresidente Onorario IMA Accademia Internazionale Mariinskaya, ramo scienze naturali, Farmacologo applicato.Latyshev O. Yu.,membro corrispondente di Intern. Professore dell'Accademia delle scienze psicologiche (IAPS) alla Cypress University e dell'Accademia russa di storia naturale, presidente dell'Accademia IMA.