Multinucleated giant cells are commonly encountered in various lesions of oral cavity. These giant cell containing lesions have overlapping histopathological features which need to be differentiated from each other. Accurate identification and categorization of these lesions based on nature, distribution and origin of giant cells is necessary. Correlation of histopathological features in relation to giant cells is required which would enable pathologists to ascertain the behavior of such lesions. Hence, characterization of giant cells in any giant cell lesion is essential to assist the clinician and researchers for precise diagnosis and management.

Dr. Kanika Sharma is an Oral Pathologist currently working as Reader in Divya Jyoti College of Dental Sciences & Research, U.P. She has completed her B.D.S. and M.D.S. from I.T.S. Dental college, Muradnagar, U.P. Her area of expertise includes potentially malignant disorders, oral cancer, connective tissue tumors and forensic odontology.