I am Dr. Himanshi Sharma, Postgraduate student, Department of Periodontology, Subharti Dental College and Hospital, Meerut. I would like to acknowledge Dr. Nitin Tomar, Associate Professor and Dr. Mayur Kaushik, Professor & Head for his constant efforts and encouragement.

Gingival crevicular fluid (GCF) is an inflammatory exudate derived from the periodontal tissues. It mainly consists of substances derived from serum, leukocytes, bacteria, activated epithelial cells, connective tissue cells, and bone cells as these possess a great potential for serving as indicators of periodontal disease and healing after therapy. GCF plays a special part in maintaining the structure of junctional epithelium and the antimicrobial defense of periodontium. Analysis of periodontal condition can be easily done by collection of GCF which is a non-invasive and relatively simple procedure.