These novel ¿¿one¿¿ and ¿¿thione¿¿ derivatives were synthesized by using established methods and were characterized by IR, 1H NMR and Mass spectroscopy in order to confirm their formation. These compounds were synthesized to screen for their antibacterial, antifungal and antitubercular activities. The compounds were found to be potent against Gram +ve, Gram ¿ve bacterial, fungal and H37Ra strains. In the view of result the most active compounds are carrying thiourea and its dominating urea derivatives.

Dr. T. Panneerselvam Is working as an Associate Professor in Arulmigu Kalasalingam College of Pharmacy, Krishnankoil, Tamilnadu. He earned Young Faculty Award 2014 and he has 08 years of teaching and research experience. His research has focused on the Design, Synthesis, and Analytical/Biological Screening of Novel Heterocyclic Derivatives.