The articles in this volume provide a comprehensive overview of our current understanding of the roles played by cellular factors in the early steps of retroviral replication. A better understanding of these functions will provide critical new insights into retrovirus-host cell interactions and is likely to prove useful for the future development of effective antiretroviral therapies.

HIV-1 Entry and Its Inhibition.- Cell Surface Receptors for Gammaretroviruses.- Alpharetrovirus Envelope-Receptor Interactions.- Targeting Retroviral and Lentiviral Vectors.- Intracellular Trafficking of HIV-1 Cores: Journey to the Center of the Cell.- The Roles of Cellular Factors in Retroviral Integration.