Preface vii
Part 1 The Biology of Obesity--Why It Occurs 1
Victor Lawrence, Section Editor
1 Energy Balance and Body Weight Homeostasis 3
2 The Genetic Basis of Obesity 13
3 Adipocyte Biology 25
4 Fetal and Infant Origins of Obesity 33
5 Metabolic Fuels and Obesity 41
Part 2 Clinical Management of the Obese Individual 51
Robert Kushner, Section Editor
6 Practical Guide to Clinical Assessment and Treatment Planning 53
7 Stages of Obesity and Weight Maintenanc 63
8 Dietary Management 71
9 Physical Activity and Exercise 81
10 Behavior Therapy 91
11 Pharmacotherapy 99
12 Surgery 109
Part 3 Clinical Management of Obesity-Related Co-morbidities 121
Sudhesh Kumar and Milan K. Piya, Section Editors
13 Diabetes and Metabolic Diseases 123
14 Obesity and Reproductive Health 133
15 Gastro-intestinal and Hepatobiliary Disease 141
16 Respiratory Disease 149
17 Obesity and Cardiovascular Disease 157
18 Obesity: Mental Health and Social Consequences 167
19 Obesity and Musculo-skeletal Disease 175
20 The Obese Patient in Hospital 181
Conversion Table 187
Index 189

Practical Manual of Clinical Obesity provides practical, accessible and expert advice on the clinical diagnosis and management of obesity and will be your perfect go-to tool in the management of your patients. Information is clear, didactic and attractively presented, with every chapter containing plenty of engaging text features such as key points, pitfall boxes, management flowcharts and case studies to enable a rapid understanding of obesity diagnosis and management. Key clinical trials and major international society guidelines are referred to throughout. Topics covered include: Assessment of the patient, including patient history, examination and investigations Patterns, risks and benefits of weight loss Evaluation of management options: diet, exercise, drugs, psychological treatments, and surgery Management of obesity related co-morbidities Practical Manual of Clinical Obesity is ideal reading for endocrinologists of all levels, as well as all other health professionals who manage obese patients such as specialist nurses, dieticians, and GP s with an interest in obesity management.