Reviews the effects of environmental contaminants on the development and degeneration of the human nervous system. Describes the adverse effects that the environment can have on neurological development, and how these effects may exhibit. Specific contaminants and their possible consequences of exposure are addressed (lead, methylmercury, alcohol), as well as specific disorders and the environmental factors associated with.

Preface Foreword by Annette Kirshner

Section I: Neurodevelopmental Disorders

1. Overview of the Role of Environmental Factors in Neurodevelopmental Disorders 2. Genetic Factors in Environmentally-Induced Disease 3. Fetal Alcohol Spectrum Disorders 4. Prenatal Infection 5. Attention Deficit-Hyperactivity Disorders 6. Organic Mercury Compounds 7. Lead 8. Endocrine Disruptors 9. Summary and Perspectives 10. Overview of Environmental Factors in Neurodegenerative Disorder

Part II: Neurodegenerative Disorders

11. Western Pacific ALS-PDC: a Prototypical Long-Latency Environment Neurodegenerative Disorder 12. Parkinson's Disease Epidemiology 13. Parkinson's Disease: Mechanisms and Biological Plausibility 14. Genetics of Parkinson's Disease 15. Environmental Risk Factors in Alzheimer Disease 16. Amyotrophic Lateral Sclerosis: Environmental Factors 17. Gene-Environment Interactions in Huntington's Disease 18. Infection, Neuroinflammation and Neurodegenerative Diseases 19. Late Effects of Early Exposures 20. Summary and Perspectives