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Fully understand the toxicological effects of prescription and OTC drugs on pregnant women and breastfed children

Drawn from the internationally recognized MotherRisk program at the University of Toronto, this authoritative resource is filled with evidence-based information and guidance that puts the risks of maternal exposure to drugs into sharp focus.

The book's clear, easy-to-follow two-part organization conveniently reviews the toxicologic effects of all major drug classes, then provides well-researched, systematic reviews of major topics that impact pharmacotherapy in pregnant and breastfeeding patients. This complete guide is your best source of information-and, consequently, your patients' best defense-against the possible ill effects of reproductive and developmental drug toxicities.

Features

• The most authoritative resource available on the maternal toxicology of prescription drugs
• Packed with evidence-based, systematic reviews of key maternal therapeutics and toxicology topics from leading peer-reviewed journals
• Complete reviews of all major drug classes, and widely used agents-plus other herbal, chemical, and radiological therapies
• Cutting-edge guidance from the world-renown MotherRisk program
• Clear, conversational tone and cohesive two-part organization that facilitates your ability to quickly identify the risks associated with specific agents and communicate this crucial information to patients
• And much more!

Gideon Koren, MD is Director of the Motherisk Program at the Hospital for Sick Children, Toronto, Ontario, Canada, and Professor of Pediatrics, Pharmacology, Pharmacy, Medicine, and Medical Genetics at the University of Toronto, Canada. The author of over 800 peer-reviewed articles, abstracts, and books, including Nausea and Vomiting of Pregnancy: State of the Art 2000 (The Motherisk Program), he is a Diplomat of the American College of Medical Toxicology and the Royal College of Physicians and Surgeons of Canada, as well as a Senior Scientist of the Canadian Institutes of Health Research.

Part I. RULES OF THUMB FOR TAKING DRUGS DURINGPREGNANCY AND BREASTFEEDING

1. TAKING DRUGS DURING PREGNANCY: HOW SAFE ARE THE UNSAFE?
Gideon Koren, MD, FRCPC, & Lavinia Schuler, MD

2. WHICH DRUGS ARE CONTRAINDICATED DURING BREASTFEEDING?: PRACTICE GUIDELINES
Myla E. Moretti, MSC, Amy Lee, MSC, Shinya Ito, MD,& Gideon Koren, MD

3. CONTINUING DRUG THERAPY WHILE BREASTFEEDING: COMMON MISCONCEPTIONSOF PATIENTS
Shinya Ito, MD, Mary Lieu, MSc, Williams Chan,& Gideon Koren, MD, FRCPC

4. CONTINUING DRUG THERAPY WHILE BREASTFEEDING: COMMON MISCONCEPTIONSOF PHYSICIANS
Gideon Koren, MD, FRCPC, Myla Moretti, MSC,& Shinya Ito, MDPart II. Drug Safety-A to Z

5. DRUG SAFETY-A TO Z
Gideon Koren, MD, FRCPCPart III. Selected Drugs, Chemicals, and Medical Conditions:Frequently Asked Questions with ConciseEvidence-Based Answers

6. SAFE USE OF VALPROIC ACID DURING PREGNANCY
Gideon Koren, MD, FRCPC, & Debbie Kennedy

7. CANCER CHEMOTHERAPY DURING PREGNANCY: CONSORTIUM OF CANCERIN PREGNANCY EVIDENCE
Michael Lishner, MD, & Gideon Koren, MD, FRCPC

8. CORTICOSTEROIDS AND NONSTEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDS)DURING PREGNANCY
Jochen G.W. Theis, MD, & Gideon Koren, MD

9. MATERNAL OBESITY AND PRENATAL RISK
Gideon Koren, MD, FRCPC

10. ANTIHISTAMINES ARE APPARENTLY SAFE DURING THE FIRST TRIMESTER
Gideon Koren, MD, FRCPC

11. CAFFEINE DURING PREGNANCY?: IN MODERATION
Gideon Koren, MD

12. ANTIMALARIAL DRUGS FOR RHEUMATOID DISEASE DURING PREGNANCY
Gideon Koren, MD

13. NICOTINE REPLACEMENT THERAPY DURING PREGNANCY
Gideon Koren, MD

14. SAFETY OF COLCHICINE THERAPY DURING PREGNANCY
Ran D. Goldman, MD, & Gideon Koren, MD, FRCPC

15. USE OF WARFARIN DURING PREGNANCY
Adrienne Einarson, RN, & RN Gideon Koren, MD, FRCPC

16. CAN WE USE ANXIOLYTICS DURING PREGNANCY WITHOUT ANXIETY?: IN MODERATION
Antonio Addis, PHARMD, Lisa R. Dolovich, PHARMD,Thomas R. Einarson, PHD, & Gideon Koren, MD, FRCPC

17. NAUSEA AND VOMITING OF PREGNANCY: EVIDENCE-BASED TREATMENT ALGORITHM
Carolyn Maltepe, Adrienne Einarson,& Gideon Koren, MD, FRCPC

18. CAN HERBAL PRODUCTS BE USED SAFELY DURING PREGNANCY?
Michael Gallo, & Gideon Koren, MD, FRCPC

19. TAKING ACE INHIBITORS DURING PREGNANCY: IS IT SAFE?
Savithiri Ratnapalan, MBBS, MRCP, & Gideon Koren, MD, FRCPC

20. PROLONGED EXPOSURE TO ANGIOTENSIN-CONVERTING ENZYMEINHIBITORS DURING PREGNANCY.FETAL TOXICITY COULD BE REVERSIBLE
A. Shrim, MD, & G. Koren, MD, FRCPC

21. LOW-MOLECULAR-WEIGHT HEPARINS DURING PREGNANCY
Ariel Many, MD, & Gideon Koren, MD, FRCPC

22. DRINKING ALCOHOL WHILE BREASTFEEDING: WILL IT HARM MY BABY?
Gideon Koren, MD, Myla Moretti, & Bhushan Kapur

23. MULTIVITAMIN SUPPLEMENTS FOR PREGNANT WOMEN: NEW INSIGHTS
Alejandro A. Nava-Ocampo, MD, MSC,& Gideon Koren, MD, FRCPC

24. FOLIC ACID AND NEURAL TUBE DEFECTS: GOOD NEWS AT LAST!
Gideon Koren, MD

25. SAFETY OF GADOLINIUM DURING PREGNANCY
Facundo Garcia-Bournissen, MD, Alon Shrim, MD,& Gideon Koren, MD, FRCPC

26. TAKING GINGER FOR NAUSEA AND VOMITING DURING PREGNANCY
Kiran Chandra, MSC, Adrienne Einarson, RN,& Gideon Koren MD, FRCPC

27. OCCUPATIONAL EXPOSURE TO INHALED ANESTHETIC: IS IT A CONCERN FOR PREGNANTWOMEN?
Samar Shuhaiber, & Gideon Koren, MD, FRCPC

28. USING CORTICOSTEROIDS DURING PREGNANCY-ARE TOPICAL, INHALED,OR SYSTEMIC AGENTS ASSOCIATED WITH RISK?
Dona Oren, MSC, Trena Nulman, MD ,Sh Ito, MD,& Gideon Koren, MD, FRCPC

29. NONSTEROIDAL ANTI-INFLAMMATORY DRUGS FOR RHEUMATOID ARTHRITISDURING PREGNANCY
Ana Florescu MSC, & Gideon Koren MD, FRCPC

30. IS TOPICAL TRETINOIN SAFE DURING THE FIRST TRIMESTER?
Lori Shapiro, MD, Giancarla Curto, MD,& Gideon Koren, MD, FRCPC

31. HOW TO ENSURE FETAL SAFETY WHEN MOTHERS USE ISOTRETINOIN (ACCUTANE)
Gideon Koren, MD, FRCPC

32. YOUNG WOMEN TAKING ISOTRETINOIN STILL CONCEIVE: ROLE OF PHYSICIANSIN PREVENTING DISASTER
Gideon Koren, MD, FRCPC

33. HYPOTHYROIDISM DURING PREGNANCY
Alejandro A. Nava-Ocampo, MD, MSC,Offie P. Soldin, PHD, MBA, & Gideon Koren, MD, FRCPC

34. EFFECTS OF PRENATAL EXPOSURE TO MARIJUANA
Eran Kozer, MD, & Gideon Koren, MD, FRCPC

35. MARIJUANA USE AND BREASTFEEDING
Josephine Djulus, MD, Myla Moretti, MSC,& Gideon Koren, MD, FRCPC

36. METFORMIN USE DURING THE FIRST TRIMESTER OF PREGNANCY: IS IT SAFE?
Gideon Koren, MD, FRCPC, Cameron Gilbert, MSC,& Maria Valois, MD, FRCPC

37. IS THE FETUS SAFE WHEN SPERMICIDES FAIL?
Gideon Koren, MD, FRCPC

38. ACID-SUPPRESSING DRUGS DURING PREGNANCY
Arieh Lalkin, MD, Laura Magee, MD, FRCPC,Antonio Addis, Pharmd, Ronen Loebstein, MD,& Gideon Koren, MD, FRCPC

39. COUNSELING PREGNANT WOMEN WHO ARE TREATED WITH PAROXETINE
Adrienne Einarson RN, & Gideon Koren MD, FRCPC

40. DISCONTINUING ANTIDEPRESSANTS AND BENZODIAZEPINES UPON BECOMING PREGNANT
Adrienne Einarson, RN, Peter Selby, MD,& Gideon Koren, MD, FRCPC

41. RISKS OF UNTREATED DEPRESSION DURING PREGNANCY
Adrienne Einarson, RN, & Gideon Koren, MD, FRCPC

42. TAKING ANTIDEPRESSANTS DURING LATE PREGNANCY-HOW SHOULD WEADVISE WOMEN?
Sanjog Kalra, MSc, Adrienne Einarson, RN,& Gideon Koren MD, FRCPC

43. TAKING ST. JOHN'S WORT DURING PREGNANCY
Ran D. Goldman, MD, & Gideon Koren, MD, FRCPC

44. TRIMETHOPRIM-SULFONAMIDE COMBINATION THERAPY IN EARLY PREGNANCY
Anna Sivojelezova, Adrienne Einarson, RN,Samar Shuhaiber, MSC, & Gideon Koren, MD, FRCPC

45. INFLUENZA VACCINATION DURING PREGNANCY
Ran D. Goldman, MD, & Gideon Koren, MD, FRCPC

46. ANTIRETROVIRAL TREATMENT OF MATERNAL HIV INFECTION
Haleh Talaie MD, MPH, Alejandro A. Nava-Ocampo, MD,& Gideon Koren, MD, FRCPC