This book offers a fundamental and comprehensive overview of nanomedicine from a systems engineering perspective, making it the first book in the field of quantitative nanomedicine based on systems theory. The book starts by introducing the concept of nanomedicine and provides basic mathematical modeling techniques that can be used to model nanoscale biomedical and biological systems. It then demonstrates how this idea can be used to model and analyze the central dogma of molecular biology, tumor growth and the immune system. Broad applications of the idea are further illustrated by Bayesian networks, multiscale and multiparadigm modeling and AFM engineering.
Nanomedicine- Dynamic Integration of Nanotechnology with Biomedical Science. Fundamental Mathematical Modeling Techniques for Nano Biosystem. A Mathematical Formulation of the Central Dogma of Molecular Biology. Systems Approach to Characterize Living Drosophila Embryos for Biomedical Investigations. Learning Signaling Pathway Structure. Computational Modeling of Tumor Biobarriers: Implications for Delivery of Nano-based Therapeutics. Multiscale-Multiparadigm Modeling and Simulation of Nanometer-Scale Systems and Processes for Nanomedical Applications. Game Theoretical Formulation of the Immune System and Inspiration for Controlled Drug Delivery. Application.