Chapter 1:Microenvironmental Effects on Tumour Progression and Metastasis; Kårstein Måseide, Tuula Kalliomäki, and Richard P. Hill Chapter 2: Role of Microenvironment on Gene Expression, Angiogenesis and Microvascular Function in Tumors; Dai Fukumura Chapter 3: Imaging of Angiogenesis In Vivo with Fluorescent Proteins: Fluorescence Imaging of Angiogenesis; Robert M. Hoffman Chapter 4: The Epigenetic Influence of the Tumor Microenvironment on Melanoma Plasticity; E. A. Seftor, P.S. Meltzer, D.A. Kirschmann, R.E.B. Seftor and M. J. C. Hendrix Chapter 5: Dynamics of Cell Adhesion Interactions during Melanoma Development; G. Li and M. Herlyn Chapter 6: Matrix Metalloproteinases: Mediators of Tumour-Host Cell Interactions; Robert J. Diaz, Alexandra Eichten, Karin E. de Visser and Lisa M. Coussens Chapter 7: Role of Brain Microenvironment in Brain Metastases; J. Grunfeld and V. K. Puduvalli Chapter 8: Influence of the Bone Microenvironment on Breast Cancer Metastasis to Bone; B. L. Eckhardt, N. Pouliot and R. L. Anderson Chapter 9: Interaction of Tumour with Host Stroma in Hepatocellular Carcinoma; D.S.R. Lockwood and D.C. Gotley Chapter 10: Dynamic Nature of Tumour-Host Interactions Within the Tumor Microenvironment; D. Nagorsen and F. M. Marincola Chapter 11: Breast Cancer Progression: A 'Vicious Vycle' of Pro-Malignancy Activities is Mediated by Inflammatory Cells, Chemokines and Cytokines; A. Ben-Baruch Chapter 12: Tumor and Host Endothelial Cell Selective Interactions and Modulation by Microenvironmental Chemokines: Tumor-Endothelial Cell Cross Talk Specificity; N. Lamerant-Fayel, C. Crola da Silva and C. Kieda Chapter 13: The Role of Chemokine Receptors, in Particular CXCR4, in Lymphoma and Carcinoma Metastasis; I. S. Zeelenberg and E.Roos Chapter 14: Energy Homeostasis and the Tumor/Host Interaction: The role of the Brain; Michael F. Wiater Chapter 15: Anti-Angiogenic and Pro-Apoptotic Effects of Dietary Restriction in Experimental Brain Cancer: Role of Glucose and Ketone Bodies; T.N. Seyfried and P. Mukherjee Chapter 16: Dietary Restriction of Specific Amino Acids Modulates Tumor and Host Interactions; G. G. Meadows and Y.-M. Fu Chapter 17: Role of Tumour Microenvironment in Chemoresistance; Yong Wei and Jessie L.-S. Au Chapter 18: Integrin-Mediated Resistance to Chemotherapy-Induced Apoptosis in Cancer Cells; R. C. Rintoul and T. Sethi Chapter 19: Bone Metastasis Microenvironment Participates in the Development of Androgen Ablation Refractoriness and Chemotherapy Resistance of Prostate Cancer Cells Residing in the Skeleton: Clinical Implications; M. Koutsilieris, R. Tenta, D. Tiblalexi, N. Pitulis, E. Sotiriou, P. Lembessis, J. Bogdanos, C. Milathianakis and A. Sourla Chapter 20: Current and Future Therapeutic Targets of the Tumour-Host Microenvironment; Jareer Kassis, Emilyn Alejandro, Victoria Virador and Elise C. Kohn Chapter 21: Bone Stromal Cells As Therapeutics Targets In Osseous Metastasis; R. A. Sikes, C. R. Cooper, G. L. Beck, F. Pruitt, M. L. Brown and G. Balian Chapter 22: Organtropism of Lung Cancer Metastasis and its Molecular Targeted Therapy; Seiji Yano, Soji Kakiuchi, Helong Zhang and Saburo Sone. Chapter 23: Maspin: A Novel Serine Protease Inhibitor; Shijie Sheng Chapter 24: Metastasis Suppressor Genes: A Brief Review of an Expanding Field; Monica M. Richert and Danny R. Welch Chapter 25: Tumor-Host Interactions at the Metastatic Site: MKK4, Signal Transduction and the Stress Response; Jonathan C. Berger, Victoria L. Robinson, Jonathan A. Hickson, Donald Vander Griend

The present multi-volume Book Series, CANCER GROWTH AND PROGRESSION, encompasses the widest possible framework of cutting edge research in the field of neoplastic pathology and other integrated fields. Normal and pathologic growth is one of the most intensively studied yet challenging areas in pathology. Thus the individual volumes in this series focus on the topics of highest scientific interest for basic and clinical researchers, pathologists, medical and surgical oncologists and allied multidisciplinary teams interested in the study of these aspects of neoplastic growth, progression and inhibition. The range of topics covered is extensive, including but not limited to autonomous growth characteristics of malignancy, phenomena of progression of malignant growth involving the various body systems, and recent advances being made in successful neoplastic inhibition and control. Cell function may be described as producing progression or regression, often found as alternating features in tumors or as variations between normal tissues and tumors. The source of regression in normal melanin producing cells may not be the same as in melanomas. These functions of living matter persist in all phyla of eumetazoans vascular plants as well as in particular species of fungi. However, homo sapiens are the eumetazoan species, which interest us the most. Normal growth processes cannot be entirely understood in all its diversity until we have a thorough knowledge of what constitutes normal growth in various organisms.