Aim of this work is to verify the role played in chromatographic technique by innovative MONOLITHS.In m R.N.A. VACCINE production: material used, technology and products for large scale production.The fact that a great producer use carbon composite in monoliths is of great interest: carbon fiber reinforcement embedded into epoxy thermoset resin.It is also verified the role played by silica products for chromatographic use and its origin (synthetic or from natural product like Rice).Related the product form Rice it is used as pharmaceutical incipient.Also in this cases other great chemicals producer in its website for SILICA GEL for chromatography report a reference related the production of silica form Rice, (not only systemic so) of interest the profile of impurity of this product if used in resin column for purification bio-pharmaceutical.And in particular the carbon content.

M. Luisetto, Dottore in Filosofia, Vicepresidente Onorario IMA Accademia Internazionale Mariinskaya, ramo scienze naturali, Farmacologo applicato.Latyshev O. Yu.,membro corrispondente di Intern. Professore dell'Accademia delle scienze psicologiche (IAPS) alla Cypress University e dell'Accademia russa di storia naturale, presidente dell'Accademia IMA.