Providing scientific and technical in-depth information in a clear format with a homogeneous structure, this text is suited for educational and self-teaching purposes as well as a reference on titanium for biomedical applications. It covers the whole area relevant to the use of titanium for implants, devices and instruments in medicine: material and surface science, physics, chemistry, biology, medicine, quality and regulatory aspects.
I Introductory Survey.- 1. A Perspective on Titanium Biocompatibility.- 2. Titanium for Medical Applications.- II Metallurgy and Fabrication; Surface and Technological Properties.- 3. Metallurgy and Technological Properties of Titanium and Titanium Alloys.- 4. Titanium-Nickel Shape Memory Alloys in Medical Applications.- 5. Characterization of Titanium Surfaces.- 6. The Corrosion Properties of Titanium and Titanium Alloys.- 7. Properties and Biological Significance of Natural Oxide Films on Titanium and Its Alloys.- III Surface Engineering.- 8. Mechanical, Thermal, Chemical and Electrochemical Surface Treatment of Titanium.- 9. Sol-Gel Coatings on Titanium.- 10. Physical and Chemical Vapor Deposition and Plasma-assisted Techniques for Coating Titanium.- 11. Production of Microfabricated Surfaces and Their Effects on Cell Behavior.- 12. Thermal Spray Coatings on Titanium.- 13. Biochemical Modification of Titanium Surfaces.- IV Biological Performance.- 14. Proteins at Titanium Interfaces.- 15. Principles of Cell Behavior on Titanium Surfaces and Their Application to Implanted Devices.- 16. Titanium in Soft Tissues.- 17. The Titanium-Bone Cell Interface In Vitro: The Role of the Surface in Promoting Osteointegration.- 18. The Titanium-Bone Interface In Vivo.- 19. Titanium Ceramics for Cell-Carriers and for Medical Applications.- V Medical Applications.- 20. Design and Engineering Criteria for Titanium Devices.- 21. Titanium for Hip and Knee Prostheses.- 22. Wear of Titanium 6-4 Alloy in Laboratory Tests and in Retrieved Human Joint Replacements.- 23. Titanium as Implant Material for Osteosynthesis Applications.- 24. Titanium for Dental Applications (I).- 25. Titanium for Dental Applications (II): Implants with Roughened Surfaces.- 26. Titanium in Cardiac and CardiovascularApplications.- 27. Titanium in Audiology.- 28. Regulatory Aspects in the Use of Titanium-based Materials for Medical Applications.- VI Appendices.- Appendix A Color Figures.- Appendix B Biographies of Editors and Authors.- Appendix C Abbreviations.- Appendix D World-Wide-Web Sites (URL Addresses).- Appendix E Index.- Appendix F Spectacles for Stereo-View of Color Figures (App. A) ............................insert at end of book.