One Health is an emerging concept that aims to bring together human, animal, and environmental health. Achieving harmonized approaches for disease detection and prevention is difficult because traditional boundaries of medical and veterinary practice must be crossed.  In the 19th and early 20th centuries this was not the case¿then researchers like Louis Pasteur and Robert Koch and physicians like William Osler and Rudolph Virchow crossed the boundaries between animal and human health. More recently Calvin Schwabe revised the concept of One Medicine.  This was critical for the advancement of the field of epidemiology, especially as applied to zoonotic diseases. The future of One Health is at a crossroads with a need to more clearly define its boundaries and demonstrate its benefits. Interestingly the greatest acceptance of One Health is seen in the developing world where it is having significant impacts on control of infectious diseases.

John S. Mackenzie was one of the volume editors of "Wildlife and Emerging Zoonotic Diseases: the Biology, Circumstances and Consequences of Cross-species Transmission", CTMI vol. 315, ISBN 978-3-540-70961-9, published in 2007

Food Safety and Food Security: a One Health Paradigm.- Food safety: at the center of a One Health approach for combating zoonoses.- The importance of a One Health approach to preventing the development and spread of antibiotic resistance.- Bovine spongiform encephalopathy: A tipping point in One Health and food safety.- Pathogenic Escherichia coli and One Health implications.- National Plans for Developing a One Health Approach.- FAO and the One Health approach.- Development of a One Health national capacity in Africa: The Southern African Centre for Infectious Disease Surveillance One Health virtual centre model.- The development of One Health approaches in the Western Pacific.- One Health approach in the South East Asia Region: Opportunities and challenges.- One Health in Mongolia.- One Health New Technologies, New Approaches and How to Implement.- Climate Change and Human Health: A One Health Approach.-Operationalizing One Health: Stone Mountain and beyond.- Building a foundation for 'One Health': an education strategy for enhancing and sustaining national and regional capacity in endemic and emerging zoonotic disease management.- Infections at the animal/human interface: shifting the paradigm from emergency response to prevention at source.- One health from a social-ecological systems perspective: Enriching social and cultural dimensions.- Subject index.