Pathogenic bacteria for human and animals have developed sophisticated weapons, termed virulence factors, to ensure their replication and persistence into their hosts. The authors in this volume show a synthesis on how the various host cellular Rho GTPases activities are manipulated by bacteria to fulfil their virulence.
Bacterial Virulence Strategies That Utilize Rho GTPases.- Extracellular Bacterial Pathogens and Small GTPases of the Rho Family: An Unexpected Combination.- Triggered Phagocytosis by Salmonella: Bacterial Molecular Mimicry of RhoGTPase Activation/Deactivation.- Regulation of Phagocytosis by Rho GTPases.- The Immunological Synapse and Rho GTPases.- Rho GTPases and the Control of the Oxidative Burst in Polymorphonuclear Leukocytes.- Clostridial Rho-Inhibiting Protein Toxins.- The Type III Cytotoxins of Yersinia and Pseudomonas aeruginosa That Modulate the Actin Cytoskeleton.- Modulation of Rho GTPases and the Actin Cytoskeleton by YopT of Yersinia.- Bacterial Toxins Activating Rho GTPases.