Human coronaviruses caused the SARS epidemic that infected more than 8000 people, killing about ten percent of them in 32 countries. This book provides essential information on these viruses and the development of vaccines to control coronavirus infections.

Coronavirus Genome Structure and Replication.- Coronavirus Transcription: A Perspective.- The Coronavirus Replicase.- Viral and Cellular Proteins Involved in Coronavirus Replication.- Coronavirus Reverse Genetics by Targeted RNA Recombination.- Coronavirus Reverse Genetics and Development of Vectors for Gene Expression.- Reverse Genetics of Coronaviruses Using Vaccinia Virus Vectors.- Development of Mouse Hepatitis Virus and SARS-CoV Infectious cDNA Constructs.