Advances in Lipid Research, Volume 14 is a five-chapter text that covers other important aspects of lipid chemistry, including an enzyme controlling cholesterol biogenesis, fatty acid activation, and lipid synthesis.
The first chapter concerns with the control of activity of ?-hydroxy-?-methylglutaryl coenzyme A reductase. The second chapter deals with the specificity, localization, and function of fatty acid activation. The third chapter describes the interaction between polyene antibiotics and sterols. This chapter specifically tackles some antibiotic activity to understand membrane function and in vivo hypolipidemic activity. The fourth chapter focuses on the lipids in plant cultures, while the fifth chapter looks into the methods of synthesis of acylglycerols and phosphoglycerides.
This book will prove useful to lipid chemists, biochemists, and researchers.

List of ContributorsPrefaceContents of Previous VolumesRegulation of HMG-CoA Reductase I. Introduction II. Unique Role of HMG-CoA Reductase in Sterol Biosynthesis III. Distribution of HMG-CoA Reductase IV. Assay of HMG-CoA Reductase Activity V. Solubilized Mammalian Liver Microsomal HMG-CoA Reductase VI. Diurnal Rhythm of Mammalian Liver HMG-CoA Reductase VII. Developmental Pattern of Rat Liver HMG-CoA Reductase VIII. Hormonal Effects on HMG-CoA Reductase IX. Modulation of HMG-CoA Reductase Activity X. Regulation of Mammalian HMG-CoA Reductase by Steroids XI. Familial Hypercholesterolemia XII. Microbial HMG-CoA Reductases XIII. Conclusion ReferencesFatty Acid Activation: Specificity, Localization, and Function I. Introduction II. Assays for Acyl-CoA Synthetases III. Reaction Mechanism IV. Substrate Specificity of Acyl-CoA Synthetases V. Subcellular Localization of Acyl-CoA Synthetases VI. Organ Distribution of Acyl-CoA Synthetases VII. Function and Regulation of Acyl-CoA Synthetases Note Added in Proof ReferencesPolyene Antibiotic-Sterol Interaction I. Introduction II. Structures and Chemical Properties of Polyene Antibiotics III. Biological Properties of Polyene Antibiotics IV. Molecular Basis of Polyene Antibiotics-Interaction with Membrane Sterols V. Polyene Antibiotics in the Study of Membrane Structure-Function Relationships VI. Concluding Remarks ReferencesThe Lipids of Plant Tissue Cultures I. Introduction II. The Plant Tissue Culture Technique III. Total Lipids of Plant Tissue Cultures IV. Fatty Acid Patterns of Lipids in Plant Tissue Cultures V. Variables Affecting the Lipids of Plant Tissue Cultures VI. Applications of Plant Tissue Cultures VII. Summary and Conclusion ReferencesSynthesis of Some Acylglycerols and Phosphoglycerides I. Introduction II. General Considerations III. Racemic Acylglycerols IV. Synthesis of Enantiomeric Acylglycerols V. Synthesis of Phosphoglycerides VI. Summary ReferencesAuthor IndexSubject Index