"Spider-Man and Deadpool - teaming up?! That's right - and the web-slinger and the Merc with a Mouth are the double act of your dreams! Legendary DEADPOOL creative team Joe Kelly and Ed McGuinness reunite to make this team-up everything you ever hoped for. But will a fledgling friendship turn sour when Wade Wilson's next target turns out to be...Peter Parker?! Someone is messing with our wascally wisecrackers, and they've blended the genes of our heroes to create one murderous, mixed-up miss named Itsy Bitsy. She's Spidey and 'Pool's "daughter" - and she has seriously creepy daddy issues! Plus: More big-name creators join the fun as Deadpool goes Hollywood, our duo shares a retro adventure, Wade & Peter meet Penn & Teller, and Spidey and 'Pool are the only ones who can save Christmas!"--Provided by publisher.

Joe Kelly broke into Marvel in 1997, adding his own style of irreverence to Deadpool and turning the title into a cult sensation. After a brief run on X-Men, Kelly departed for DC Comics, where he delivered award-winning work on Action Comics and Superboy. He has since returned to Marvel, collaborating with the “Spider-Man Brain Trust” and penning several memorable arcs on Amazing Spider-Man. Along with several fellow comic creators, Kelly established Man of Action, the studio that has produced the Ben 10 animated series.
Artist Ed McGuinness came to prominence with his work on Harris Comics’ Vampirella and Marvel’s Deadpool. At Awesome Entertainment, McGuinness participated in a Fighting American revamp with writer Jeph Loeb, who would become a longtime collaborator. A short run on WildStorm’s Mr. Majestic led to a longer one on DC Comics’ Superman and the launch of Superman/Batman with Loeb. Back at Marvel, McGuinness reunited with Loeb for Fallen Son: The Death of Captain America, Hulk and Avengers: X-Sanction before launching Amazing X-Men with Jason Aaron. McGuinness has reteamed with his Deadpool scribe Joe Kelly for Spider-Man/Deadpool and with Aaron on a blockbuster relaunch of Avengers.