Stimuli-Responsive Nanocarriers for Targeted Drug Delivery presents a comprehensive overview of the most significant physical and chemical stimuli-responsive drug delivery systems. This book reviews targeted and controlled drug delivery systems and how nanocarriers can be used to improve the pharmacokinetics of drugs in biological systems, such as increasing utilization rate and reducing toxicity and side effects. After a key introduction to the topic, a range of nanocarrier types is assessed before exploring the clinical translation challenges and considerations involved.This book is a useful resource for researchers and postgraduate students in the fields of materials science, nanotechnology, pharmaceutical science, and medicinal chemistry.
- Offers an in-depth look at the basic and fundamental aspects of stimuli-responsive materials, mechanisms, structure, synthesis and properties
- Provides information about well-defined categorization for stimuli-responsive drug delivery system based on different triggering mechanisms to its reader
- Reviews basic concepts and the latest research involving advances in stimuli-responsive drug delivery systems in controlled-release drugs
- Discusses novel approaches and challenges for scaling-up and commercialization of stimuli-responsive polymers

Muhammad Raza Shah is a full professor at the International Center for Chemical and Biological Sciences, HEJ Research Institute of Chemistry, University of Karachi, Pakistan. He is also the Head of the Center for Bioequivalence Studies and Clinical Research. He is a recipient of several awards, including the Tamgha-i-Imtiaz Award from the President of Pakistan, the Salam Prize, the Professor Atta ur Rahman Gold Medal, and the Dr M Raziuddin Siddiqi Prize, by the Pakistan Academy of Sciences, for scientists under 40 years of age, in the field of chemistry. Professor Shah has authored six books and edited four books, in addition to contributing over 350 peer-reviewed journal papers. One of his authored books was declared as best book of 2017 by the Government of Pakistan's Higher Education Commission.Tooba Jabri is a Ph.D scholar at H.E.J Research Institute of Chemistry, University of Karachi, in Pakistan. Her specialization is in organic chemistry. Her research interests include design and development of nanomaterials, drug delivery, organic synthesis and polymeric materials. She has series of publications and patents and is involved in several writing projects and has been part of the design and editing of a handbook on laboratory safety (currently under publication). She worked as a secondment in INFUSION project HORIZON 2020 at Cardiff University, UK. She has also received an indigenous scholarship from the Higher Education Commission Pakistan.Maria Khalid is currently pursuing her Ph.D in Organic Chemistry at H.E.J Research Institute of Chemistry, University of Karachi. Her research Interests include nanomaterials, soft polymeric materials, peptides, and drug delivery. She has a number of publications and patents in the abovementioned areas. Maria has authored the primary science textbook series "Explore your world (ERI Publication). She has also been a part of the development of "Handbook of Laboratory safety by Elsevier.

1. Introduction 2. Endogenous and Exogenous Stimuli-Responsive Nanoscale Drug Delivery Systems 3. pH Responsive Nanocarriers for Drug Delivery 4. Temperature Responsive Nanocarriers for Drug Delivery 5. Light Responsive Nanocarriers for Drug Delivery 6. Redox Responsive Nanocarriers for Drug Delivery 7. Enzyme Responsive Nanocarriers for Drug Delivery 8. Ultrasound Responsive Nanocarriers for Drug Delivery 9. Magnetic Field Responsive Nanocarriers for Drug Delivery 10. Electrical Responsive Nanocarriers for Drug Delivery 11. Dual and Multiple Responsive Nanocarriers for Drug Delivery 12. Stimuli-Responsive Nanocarriers in Clinical Translation