A Mechanistic Approach to Medicines for Tuberculosis Nanotherapy examines drug carrier development for controlled, targeted, pH and stimuli responsive drug releases for tuberculosis. The book provides in-depth information about mycobacterium tuberculosis, tuberculosis formation, and synthetic procedures for carrier synthesis, characterizations and mechanistic approaches. Key topics include the properties and functions of nanomedicines and how they might be applied for clinical diagnosis and treatment. Emphasis is placed on the basic fundamentals, biomaterial formulations, design principles, fabrication techniques, and transitioning bench-to-bed clinical applications.
This book is useful for new researchers who focus on nanomedicine, stem cell therapy and bone tissue engineering. In addition, it introduces experienced researchers and clinicians to key trends, thus increasing their knowledge in drug discovery for tuberculosis and nanomedicine.
1. Basics of tuberculosis disease and Principles of treatment and their effects2. The pulmonary administration route: Advantages and challenges3. Alternative non-invasive routes of administration of nanomedicines against Tuberculosis4. Approaches of designing nanocarriers for Tuberculosis drug delivery5. Controlled Strategies towards the nanotherapy of tuberculosis6. Tuberculosis disease targeted nanotherapy7. pH, Thermo and stimuli responsive nanotherapy beside anti-tuberculosis drug delivery8. Nanotheranostics management of Drug resistant tuberculosis9. Nanomedicine for bone tuberculosis10. Current approach of Stem Cell Medicine in Drug-Resistant Tuberculosis11. Adjuvant nanoformulations for delivery of anti-tuberculosis vaccine patients12. Sensors development for tuberculosis Detection13. In-silico and computational approaches of inhibitor design14. Inhibitors treatment against Tuberculosis treatment15. Challenges and future perspectives