1. Genetic Testing Expanded Aad Tibben and Barbara Bowles Biesecker 2. Responses to Sequencing Information Leslie Biesecker and Barbara Bowles Biesecker 3. Consenting Patients to Genome Sequencing Heidi Carmen Howard 4. Judgement and Decision Making in Genome Sequencing William Klein and Barbara Bowles Biesecker 5. Uncertainties in Genome Sequencing Barbara Bowles Biesecker and Aad Tibben 6. Direct to Consumer Genome Sequencing Cecile Janssens 7. Precision (Personalized) Medicine Marc S. Williams 8. Genetic Counseling and Genomic Sequencing Barbara Bernhardt 9. Genome Sequencing in Pediatrics Candice Cornelis 10. Genome Sequencing in Prenatal Testing and Screening Sam Riedijk 11. Genome Sequencing in Psychiatric Disorders Christian Bouwkamp 12. Ethical Issues in Genome Sequencing Guido de Wert 13. Summary of Key Areas for Research Barbara Bowles Biesecker and Aad Tibben