volume 1. Epidemiology, biology, and therapy

I. GENERAL APPLICATIONS 1. Brain Metastases - Albert S. Braverman 2. Epidemiology of Central Nervous System Metastases - Xiao-tang Kong, Daniela Alexandru, and Daniela A. Bota 3. Involvement of the CXCL12/CXCR4/CXCR7 Axis in Brain Metastases - Chiara Calatozzolo, Emilio Ciusani, Elena Corsini, Francesco Di Meco, Bianca Pollo, and Andrea Salmaggi 4. Non-Uniform Distribution of Metastatic Intracranial Tumors in Cancer Patients - Carlo C. Quattrocchi, Yuri Errante, Carlo Augusto Mallio, and Bruno Beomonte Zobel 5. Targeting Angiogenesis, Enhancing Radiosensitization and Crossing the Blood - Brain Barrier for Brain Metastases - Emmanouil Fokas 6. Second Malignancies in Children following Treatment for Neuroblastoma - Albert Garaventa, and Bruno De Bernardi 7. The Role of Chemotherapy in Metastatic Brain Tumors - Lynn Mubita and Steven N. Kalkanis 8. Multiple Metastases to Brain from Primary Cancers: Whole Brain Radiotherapy - Hany Soliman, Arjun Sahgal and Mary Tsao 9. Synoval Sarcoma Metastasized to the Brain - Nikolaos Sakellaridis and Lygeri Sakellaridi

II. BRAIN METASTASES FROM NON-SMALL CELL LUNG CARCINOMA 10. Multiple Small Brain Metastases with Limited Focal Brain Edema from Non-Small Cell Lung Cancer with Epidermal Growth Factor Receptor Mutations - Akimasa Sekine 11. Brain Metastases of Patients with Lung Adenocarcinoma: Epidermal Growth Factor Receptor Mutations and Response to Whole-Brain Radiation Therapy - Shang-Gin Wu and Jin-Yuan Shih 12. Metastatic Spread of Lung Cancer to Brain and Liver: Role of CX3CR1 - David James Pinato and Francesco A. Mauri 13. Solitary Brain Metastasis from Non-Small Cell Lung Cancer: Treatment with Linac-Based Stereotactic Radiosurgery - Filippo Alongi, Umberto Ricardi, and Marta Scorsetti  14. Brain Metastases from Non-Small Cell Lung Cancer: Clinical Benefits of Erlotinib and Gefitinib - M. Houman Fekrazad, Omid Sanaei, Julie E. Bauman, and Dennie V. Jones, Jr. 15. Bispecific Targeted Toxin Dtategf against Metastatic NSCL Brain Tumors - Walter A. Hall, Jun Huang, Yan Michael Li and Daniel A. Vallera 16. Intracranial Disease in Patients with Non-Small Cell Lung Cancer: Treatment with Erlotinib - Mazhar Ajaz, Fiona McDonald, Jaishree Bhosle, Paola Bordi, and Mary O'Brien 17. Radiation Management of Synchronous Brain Metastases from Non-Small Cell Lung - Allison Ashworth, David Palma, and George Rodrigues 18. Brain Metastases after Prophylactic Cranial Irradiation in Patients with Small Cell Lung Cancer Responding to Chemotherapy - Tak Hing Patricia Tai, Avi Assouline, Kurian Joseph, Joseph Siu-kie Au, and Edward Yu

III. BRAIN METASTASES FROM SMALL CELL LUNG CARCINOMA 19. Brain Metastases from Small-Cell Lung Cancer with High Levels of Placental Growth Factor - Yu-Hua Chen and Bo Li 20. Brain Metastases from Lung Cancer - Amol J. Ghia and Ritsuko Komaki 21. Lambert-Eaton Myasthenic Syndrome and Brain Metastases from Occult Small Cell Lung Carcinoma: a Clinician's Perspective - Arunansu Talukdar, Nikhil Sonthalia, Sayantan Ray, and Supratip Kundu