Offers coverage of the development of protein purification processes for large-scale commercial operations, and addresses process development, scale-up, applications and mathematical descriptions. Technologies currently used at the commercial scale are covered in depth.

"Organization and Strategy, Roger G. Harrison Analytical Considerations in the Development of Protein Purification Processes, Vincent Anicetti and William S. Hancock Cell Breakage, Cady R. Engler Crossflow Membrane Filtration, Zhi-Guo Su and Clark K. Cotton Liquid-Liquid Extraction, Dennis J. Kubek Differential Precipitation of Proteins: Science and Technology, Fred Rothstein Conventional Chromatography, John M. Simpson Biospecific Affinity Chromatography, Nikos K. Harakas Freeze Drying: A Practical Overview, Larry A. Gatlin and Steven L. Nail ".